ONCE › Ingredients

Every ingredient, and why it is there

Nineteen actives, every milligram printed on the panel, no proprietary blends. Each page below covers what the ingredient is, why it is in the formula, why that exact dose, the form we require from the manufacturer, and where the evidence stops.

Skin

Collagen peptides
Collagen peptides
5 g
Collagen is the protein that holds skin firm. Hydrolyzed collagen peptides…
Hyaluronic acid
Hyaluronic acid
120 mg
Hyaluronic acid is a molecule your skin already makes. It holds water, up …
Ceramides (glucosylceramide)
Ceramides (glucosylceramide)
30 mg
Ceramides are the lipids that make up your skin's barrier, the layer that …
Vitamin C
Vitamin C
500 mg
Vitamin C is a required cofactor for collagen synthesis. Your body physica…
Astaxanthin
Astaxanthin
6 mg
Astaxanthin is the carotenoid that makes salmon and shrimp pink. It is a p…

Hair & nails

Biotin
Biotin
2,500 mcg
Biotin is a B vitamin involved in keratin production, the protein that mak…
Zinc and copper
Zinc and copper
11 mg zinc, 1 mg copper
Zinc supports skin, hair and nail structure and immune function. Copper is…

Sleep

Magnesium bisglycinate
Magnesium bisglycinate
300 mg elemental
Magnesium is involved in hundreds of enzymatic reactions, including the on…
Glycine
Glycine
3 g
Glycine is an amino acid that acts as an inhibitory neurotransmitter. It a…
L-Theanine
L-Theanine
200 mg
L-theanine is an amino acid found in tea leaves. It promotes a relaxed but…
Chamomile extract
Chamomile extract
150 mg
Chamomile is the oldest sleep remedy in the cabinet. Its relevant compound…

Gut

Digestive enzyme blend
Digestive enzyme blend
85 mg
Digestive enzymes break food into pieces small enough to absorb. The blend…
Probiotic
Probiotic
2 billion CFU
A probiotic is a live organism taken in an amount intended to support the …
Ginger root
Ginger root
75 mg
Ginger is one of the best evidenced botanicals for settling the stomach, w…
Peppermint leaf
Peppermint leaf
75 mg
Peppermint is traditionally used for digestive comfort, and peppermint oil…

Restore

Creatine monohydrate
Creatine monohydrate
3 g
Creatine is the most studied supplement in existence. It helps your cells …
NMN (nicotinamide mononucleotide)
NMN (nicotinamide mononucleotide)
500 mg
NMN is a direct precursor to NAD+, a coenzyme every cell uses for energy a…

Hormones

Myo-inositol
Myo-inositol
2 g
Myo-inositol is a sugar alcohol involved in insulin signalling and hormona…
All of it in one scoop, before bed.ONCE DUSK · night time beauty + rest

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. This page is educational and is not medical advice. If you are pregnant, nursing, or taking prescription medication, speak to your doctor first.